This hypothesis (suggested by Simon Baron-Cohen), called the ‘extreme male brain’ theory, postulates that males are at higher risk for Autism as a result of in-utero exposure to steroid hormones called androgens. This exposure, the theory goes, accentuates the male-like tendency to recognize patterns in the world (systemizing behavior) and diminishes the female-like capacity to perceive social cues (socializing behavior). Put simply, boys are already part way along the spectrum, and if they are exposed to excessive androgens in the womb, these hormones can push them into the diagnostic range.
- Elevated fetal steroidogenic activity in autism - PubMed
- Foetal oestrogens and autism - PubMed
- Autism: the empathizing-systemizing (E-S) theory - PubMed
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A critique (although it doesn’t reject the premise, but says we can’t call it either way, but also says that most certainly estrogens play a role in explaining why males exhibit autism symptoms more often)